Outlook displays this message when another process uses the OST file or the file cannot be opened. End the Outlook and Skype processes, test safe mode and repair Office. Test Cached Exchange Mode next. Converter software exports the mail when Outlook still refuses the file.
Outlook OST file is in use and cannot be accessed is the message that appears when Outlook starts and cannot open your offline mailbox. Outlook tells you to close any application that uses the file and restart the computer.
This guide explains five tests from a Task Manager check to software that exports the mail.
Microsoft publishes the Office repair steps in its repair article for Office apps.
What Causes the OST Access Error?
Microsoft documents no single cause for the message. Two Microsoft Q&A threads from 2018 give the process and cached mode clues. Safe mode tests the add in clue:
- Another process. In one Microsoft Q&A thread from March 2018 the user saw the error after an update restart while Skype for Business was still starting. That user reported that letting Skype for Business finish first avoided the errors. Outlook also reported that only one version can open at a time.
- Damaged Office files. The accepted answer in that thread was a restart followed by an Office repair.
- Add ins. Microsoft documents no add in cause for this message. Safe mode shows whether an add in is involved.
- Cached mode. A second Microsoft Q&A thread from January 2018 listed Cached Exchange Mode off as a test. That poster reported no result.
No Microsoft article names this exact message. Both Microsoft Q&A threads date from 2018 and one reply in the first said the repair resolved the issue.
Which Startup Clue do You See?
Match your clue to a method first:
| Startup Clue | First Test | Method |
|---|---|---|
| Skype for Business starts with Outlook | End the processes | Method #1 |
| Outlook opens in safe mode | Add ins | Method #2 |
| Error follows an update or a crash | Office repair | Method #3 |
| Exchange account in cached mode | Mode test | Method #4 |
| OST file never opens | Converter software | Method #5 |
5 Ways to Fix Outlook OST File is in Use and Cannot be Accessed
Four methods use Windows and Outlook settings. Software handles the fifth:
| Option | Source | Catch |
|---|---|---|
| End Processes | Community answer | Needs a restart |
| Safe Mode | Microsoft article | Disables add ins |
| Office Repair | Microsoft article | Repairs the full suite |
| Cached Mode Test | Q&A thread and Microsoft article | Exchange accounts only |
| Converter Software | Product guide | Trial limit |
Method #1: End Outlook Processes in Task Manager (Free)
Another process can use the file when Outlook starts. Six steps release it:
- Close every Outlook window and save your work.
- Press Ctrl + Shift + Esc to open Task Manager.
- Open the Processes tab and find Microsoft Outlook.
- Select the entry and press End task.
- Repeat for Skype for Business or Lync when they appear in the list.
- Restart the computer and open Outlook.
Note: A community answer in the second thread named Communicator, Lync and ucmapi as processes to close. Let Skype for Business finish starting before you open Outlook because the person who asked in the first thread reported that order avoided the errors.
Method #2: Open Outlook in Safe Mode and Disable Add Ins (Free)
Microsoft states in its safe mode article that safe mode disables add ins. Six steps test them:
- Press Windows + R on the keyboard.
- Enter
outlook.exe /safeand press OK. - Choose your profile in the dialog and press OK.
- Open File then Options and select Add-ins.
- Choose COM Add-ins in the Manage box and press Go.
- Clear the boxes and close Outlook before you open it again as usual.
Note: Microsoft's safe mode article suggests the full path to Outlook when Windows cannot find the command and gives the Office version folder as its example. Tick the add ins again one at a time to find the one that causes the error.
Method #3: Repair Office From Apps and Features (Free)
Microsoft describes the first repair option as a check that detects and replaces corrupted files. One Microsoft Q&A thread accepted this repair after a restart as its answer. Five steps start it:
- Right click Start and open Apps and Features.
- Find your Office entry in the list and press Modify.
- Choose Quick Repair and press Repair.
- Restart the computer when the repair ends.
- Open Outlook and repeat steps 1 to 3 but choose Online Repair if the error remains.
Note: Microsoft's repair article states that repairing one Office app repairs the full suite. Microsoft describes Online Repair as the option that makes sure everything gets fixed.
Method #4: Switch Off Cached Exchange Mode to Test the Error (Free)
One community answer in the second thread listed this test for the error. According to the Microsoft article on Cached Exchange Mode the mode downloads your mail to an Outlook data file and does not apply to POP or IMAP accounts. Six steps test it:
- Close Outlook and go to Control Panel.
- Open Mail (Microsoft Outlook) and press Email Accounts.
- Select your Exchange account on the Email tab and press Change.
- Clear Use Cached Exchange Mode under Offline Settings.
- Press Next and then Finish.
- Open Outlook and tick the box again once the error is gone.
Note: Microsoft recommends the mode as the default for Exchange accounts and states that the setting is missing when an administrator disables it.
Method #5: Convert the OST File to PST With EmailDoctor OST to PST Converter (Trial Limit Applies)
Product guide says EmailDoctor OST to PST Converter opens corrupt and orphan OST files with no Outlook and no Exchange profile. Use a copy so the original file remains safe.
Open the OST Copy in the Software
Three steps add the file:
- Open the converter and press Add File on the first screen.
- Choose Select File in the dialog and use the ... button to browse to the copy.
- Select Quick scan and press Add. Switch to Advanced when the preview shows no data.
Check the Folders and Save the PST File
Three steps finish the export:
- Look through the folder list after the scan because bold folders contain data.
- Press Export and select PST as the output.
- Select the destination folder with Browse and press Export.
Note: Product guide puts the trial export at 25 items for every folder. Test one folder before the full export.
What do the Results Tell You?
Compare the outcome before the next test:
| Your Result | What It Means | Go To |
|---|---|---|
| Error ends after closing the processes | Points to another process | Start Skype first |
| Outlook opens in safe mode | Points to an add in | Remove that add in |
| Error ends after the repair | Points to damaged Office files | Confirm the mail opens |
| Error ends with the mode off | Points to the mode setting | Use the Also Read guide on the configuration error |
| Error returns after every test | Unreadable OST file | Method #5 |
Frequently Asked Questions
What Does the OST Access Message Mean?
Outlook cannot open the offline mailbox file because another process uses it or the file is unreadable. Microsoft lists no cause in its documentation.
Do I Need to Restart the Computer?
Yes. Outlook's message tells you to restart the computer. Restart first and use the methods when the message returns.
Will I Lose Emails if I Disable Cached Exchange Mode?
No. Microsoft describes the mode as a download of your mail to an Outlook data file. Your mailbox remains on the server. Switch the mode on after the test because Microsoft recommends it.
Does Safe Mode Delete My Add Ins?
No. Microsoft states that safe mode disables add ins. Tick them again in the add ins list to enable them.
Does the Office Repair Delete My Mail?
Microsoft describes the first repair option as detecting and replacing corrupted Office files. Microsoft's article does not mention mail.
Can Software Open the OST File Without Outlook?
Yes. Product guide says Outlook is not required.
What is the Trial Export Limit?
Product guide lists 25 items in every folder for the trial.
Author’s Verdict
Close the Outlook and Skype processes first because Microsoft Q&A users tied the error to another process. Test safe mode and repair Office next.
Test Cached Exchange Mode on Exchange accounts only. Choose converter software if the OST file never opens.
Backup the OST file before any repair.
- End the Outlook and Skype processes first.
- Test safe mode and repair Office.
- Test Cached Exchange Mode on Exchange accounts.
- Converter software exports mail from an OST file that never opens.